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Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A re...

Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72842400

Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A receptors

About this item

Full title

Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A receptors

Publisher

Ottawa, Canada: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2002-12, Vol.80 (12), p.1158-1166

Language

English

Formats

Publication information

Publisher

Ottawa, Canada: NRC Research Press

More information

Scope and Contents

Contents

In vivo microdialysis in conscious rats was used to examine the effect of clozapine on serotonin (5-hydroxy tryptamine, 5-HT) efflux in the prefrontal cortex and dorsal raphe nucleus and dopamine efflux in the prefrontal cortex. Both systemic and local administration of clozapine (systemic,10 or 20 mg/kg, i.p.; local, 100 μM) increased 5-HT efflux...

Alternative Titles

Full title

Effects of clozapine on the efflux of serotonin and dopamine in the rat brain: the role of 5-HT1A receptors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72842400

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72842400

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/y02-150

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