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Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key media...

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key media...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72970023

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia

About this item

Full title

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia

Publisher

Alexandria, VA: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2003-02, Vol.52 (2), p.227-231

Language

English

Formats

Publication information

Publisher

Alexandria, VA: American Diabetes Association

More information

Scope and Contents

Contents

In peripheral tissues, insulin signaling involves activation of the insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase (PI3K) enzyme system. In the hypothalamus, insulin functions with leptin as an afferent adiposity signal important for the regulation of body fat stores and hepatic glucose metabolism. To test the hypothesis that hypoth...

Alternative Titles

Full title

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72970023

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72970023

Other Identifiers

ISSN

0012-1797

DOI

10.2337/diabetes.52.2.227

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