Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key media...
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
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Alexandria, VA: American Diabetes Association
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Language
English
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Alexandria, VA: American Diabetes Association
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Contents
In peripheral tissues, insulin signaling involves activation of the insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase (PI3K) enzyme system. In the hypothalamus, insulin functions with leptin as an afferent adiposity signal important for the regulation of body fat stores and hepatic glucose metabolism. To test the hypothesis that hypoth...
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Full title
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
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TN_cdi_proquest_miscellaneous_72970023
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72970023
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ISSN
0012-1797
DOI
10.2337/diabetes.52.2.227