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Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells: Disarming by Neutrophil Serine Prot...

Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells: Disarming by Neutrophil Serine Prot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73026867

Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells: Disarming by Neutrophil Serine Proteinases

About this item

Full title

Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells: Disarming by Neutrophil Serine Proteinases

Publisher

United States: Am Thoracic Soc

Journal title

American journal of respiratory cell and molecular biology, 2003-03, Vol.28 (3), p.339-346

Language

English

Formats

Publication information

Publisher

United States: Am Thoracic Soc

More information

Scope and Contents

Contents

Proteinase-activated receptor (PAR)-2 is cleaved within its aminoterminal extracellular domain by serine proteinases such as trypsin, unmasking a new aminoterminus starting with the sequence SLIGKV, which binds intramolecularly and activates the receptor. PAR-2 has been reported to be involved in inflammation within the lungs. We show that PAR-2 is...

Alternative Titles

Full title

Proteinase-Activated Receptor-2 and Human Lung Epithelial Cells: Disarming by Neutrophil Serine Proteinases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73026867

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73026867

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.4908

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