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Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice

Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73101310

Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice

About this item

Full title

Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

Journal title

Journal of neuropathology and experimental neurology, 2003-03, Vol.62 (3), p.280-291

Language

English

Formats

Publication information

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

More information

Scope and Contents

Contents

Accumulating evidence suggests that among the 3 human apolipoprotein E (apoE) isoforms encoded by the human APOE gene, the 4 allele may act to exacerbate brain damage in humans and animals. This study aimed to compare the isoform-specific vulnerability conferred by human apoE to ischemic brain damage, using mice expressing human apoE isoforms (apoE...

Alternative Titles

Full title

Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73101310

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73101310

Other Identifiers

ISSN

0022-3069

E-ISSN

1554-6578

DOI

10.1093/jnen/62.3.280

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