Enhancement of therapeutic protein in vivo activities through glycoengineering
Enhancement of therapeutic protein in vivo activities through glycoengineering
About this item
Full title
Author / Creator
Elliott, Steve , Lorenzini, Tony , Asher, Sheilah , Aoki, Ken , Brankow, David , Buck, Lynette , Busse, Leigh , Chang, David , Fuller, Janis , Grant, James , Hernday, Natasha , Hokum, Martha , Hu, Sylvia , Knudten, Andrew , Levin, Nancy , Komorowski, Renee , Martin, Frank , Navarro, Rachell , Osslund, Timothy , Rogers, Gary , Rogers, Norma , Trail, Geri and Egrie, Joan
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Delivery of protein therapeutics often requires frequent injections because of low activity or rapid clearance, thereby placing a burden on patients and caregivers. Using glycoengineering, we have increased and prolonged the activity of proteins, thus allowing reduced frequency of administration. Glycosylation analogs with new N-linked glycosylatio...
Alternative Titles
Full title
Enhancement of therapeutic protein in vivo activities through glycoengineering
Authors, Artists and Contributors
Author / Creator
Lorenzini, Tony
Asher, Sheilah
Aoki, Ken
Brankow, David
Buck, Lynette
Busse, Leigh
Chang, David
Fuller, Janis
Grant, James
Hernday, Natasha
Hokum, Martha
Hu, Sylvia
Knudten, Andrew
Levin, Nancy
Komorowski, Renee
Martin, Frank
Navarro, Rachell
Osslund, Timothy
Rogers, Gary
Rogers, Norma
Trail, Geri
Egrie, Joan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_73147711
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73147711
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt799
