PI3K in lymphocyte development, differentiation and activation
PI3K in lymphocyte development, differentiation and activation
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Key Points
Recent mouse-knockout experiments have indicated crucial, non-redundant functions for individual phosphoinositide 3-kinase (PI3K) subunits.
p85α and p110δ have crucial roles in B-cell development, differentiation and function.
p110δ, but not p85α, has an important role in T-cell activation and differentiation.
p110γ regulates...
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Full title
PI3K in lymphocyte development, differentiation and activation
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TN_cdi_proquest_miscellaneous_73154364
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73154364
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri1056
