The Hepatitis C Virus p7 Protein Forms an Ion Channel That Is Inhibited by Long-Alkyl-Chain Iminosug...
The Hepatitis C Virus p7 Protein Forms an Ion Channel That Is Inhibited by Long-Alkyl-Chain Iminosugar Derivatives
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
We show that hepatitis C virus (HCV) p7 protein forms ion channels in black lipid membranes. HCV p7 ion channels are inhibited by long-alkyl-chain iminosugar derivatives, which have antiviral activity against the HCV surrogate bovine viral diarrhea virus. HCV p7 presents a potential target for antiviral therapy.
Alternative Titles
Full title
The Hepatitis C Virus p7 Protein Forms an Ion Channel That Is Inhibited by Long-Alkyl-Chain Iminosugar Derivatives
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_73302565
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73302565
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1031527100
