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Accentuated T Helper Type 2 Airway Response after Allergen Challenge in Cyclooxygenase-1-/- but Not...

Accentuated T Helper Type 2 Airway Response after Allergen Challenge in Cyclooxygenase-1-/- but Not...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73305293

Accentuated T Helper Type 2 Airway Response after Allergen Challenge in Cyclooxygenase-1-/- but Not Cyclooxygenase-2-/- Mice

About this item

Full title

Accentuated T Helper Type 2 Airway Response after Allergen Challenge in Cyclooxygenase-1-/- but Not Cyclooxygenase-2-/- Mice

Publisher

New York, NY: Am Thoracic Soc

Journal title

American journal of respiratory and critical care medicine, 2003-06, Vol.167 (11), p.1509-1515

Language

English

Formats

Publication information

Publisher

New York, NY: Am Thoracic Soc

More information

Scope and Contents

Contents

Acute pharmacologic inhibition of cyclooxygenase (COX)-1 or -2 during allergen sensitization and exposure leads to enhanced T helper type 2 (Th2) airway responses. COX-1 and -2 play functionally distinct roles in lymphocyte development, and consequently, genetic deficiency of either enzyme, as opposed to acute pharmacologic inhibition, may modulate...

Alternative Titles

Full title

Accentuated T Helper Type 2 Airway Response after Allergen Challenge in Cyclooxygenase-1-/- but Not Cyclooxygenase-2-/- Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73305293

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73305293

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.200211-1383OC

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