Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute...
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
We report here that individuals with Noonan syndrome and juvenile myelomonocytic leukemia (JMML) have germline mutations in
PTPN11
and that somatic mutations in
PTPN11
account for 34% of non-syndromic JMML. Furthermore, we found mutations in
PTPN11
in a small percentage of individuals with myelodysplastic syndrome (MDS) and
de...
Alternative Titles
Full title
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
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TN_cdi_proquest_miscellaneous_73325101
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73325101
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng1156
