HSP90 at the hub of protein homeostasis: emerging mechanistic insights
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Key Points
Heat shock protein 90 (HSP90) is an abundant and evolutionarily highly conserved molecular chaperone that regulates the maturation, activity and stability of a wide range of substrate proteins (clients). In eukaryotes, HSP90 is essential for survival during heat and other stresses, but it also has a central role in a vast array of sig...
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Full title
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
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TN_cdi_proquest_miscellaneous_733399883
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733399883
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ISSN
1471-0072,1471-0080
E-ISSN
1471-0080
DOI
10.1038/nrm2918
