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Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalo...

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733443229

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response

About this item

Full title

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response

Publisher

England: Future Medicine Ltd

Journal title

Pharmacogenomics, 2010-04, Vol.11 (4), p.537-546

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

The antidepressant escitalopram (
-CIT) is metabolized by the cytochrome-P450 (CYP) enzymes CYP 2D6, 2C19 and 3A4. This study evaluated the impact of
,
and
genetic polymorphisms on plasma concentrations of
-CIT and patient treatment response.
A total of 100 patients diagnosed with major depressive disorder were recruited to the st...

Alternative Titles

Full title

Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733443229

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733443229

Other Identifiers

ISSN

1462-2416

E-ISSN

1744-8042

DOI

10.2217/pgs.09.168

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