Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independent...
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
About this item
Full title
Author / Creator
Sanz, Alberto , Soikkeli, Mikko , Portero-Otín, Manuel , Wilson, Angela , Kemppainen, Esko , McIlroy, George , Ellilä, Simo , Kemppainen, Kia K , Tuomela, Tea , Lakanmaa, Matti , Kiviranta, Essi , Stefanatos, Rhoda , Dufour, Eric , Hutz, Bettina , Naudí, Alba , Jové, Mariona , Zeb, Akbar , Vartiainen, Suvi , Matsuno-Yagi, Akemi , Yagi, Takao , Rustin, Pierre , Pamplona, Reinald and Jacobs, Howard T
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Mutations in mitochondrial oxidative phosphorylation complex I are associated with multiple pathologies, and complex I has been proposed as a crucial regulator of animal longevity. In yeast, the single-subunit NADH dehydrogenase Ndi1 serves as a non-proton-translocating alternative enzyme that replaces complex I, bringing about the reoxidation of i...
Alternative Titles
Full title
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
Authors, Artists and Contributors
Author / Creator
Soikkeli, Mikko
Portero-Otín, Manuel
Wilson, Angela
Kemppainen, Esko
McIlroy, George
Ellilä, Simo
Kemppainen, Kia K
Tuomela, Tea
Lakanmaa, Matti
Kiviranta, Essi
Stefanatos, Rhoda
Dufour, Eric
Hutz, Bettina
Naudí, Alba
Jové, Mariona
Zeb, Akbar
Vartiainen, Suvi
Matsuno-Yagi, Akemi
Yagi, Takao
Rustin, Pierre
Pamplona, Reinald
Jacobs, Howard T
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_733500100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733500100
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0911539107
