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Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance

Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733559918

Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance

About this item

Full title

Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance

Author / Creator

Publisher

England: Taylor & Francis Group

Journal title

Journal of biopharmaceutical statistics, 2010-07, Vol.20 (4), p.745-758

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis Group

More information

Scope and Contents

Contents

The standard intent-to-treat (ITT) approach can lead to erroneous conclusions about treatment efficacy in noninferiority trials with noncompliance. Per-protocol and as-treated analyses are also known to result in biased comparisons of treatment effects. Alternative statistical methods are therefore needed to better address the effects of noncomplia...

Alternative Titles

Full title

Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733559918

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733559918

Other Identifiers

ISSN

1054-3406

E-ISSN

1520-5711

DOI

10.1080/10543401003618157

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