Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance
Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance
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Publisher
England: Taylor & Francis Group
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Language
English
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Publisher
England: Taylor & Francis Group
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Scope and Contents
Contents
The standard intent-to-treat (ITT) approach can lead to erroneous conclusions about treatment efficacy in noninferiority trials with noncompliance. Per-protocol and as-treated analyses are also known to result in biased comparisons of treatment effects. Alternative statistical methods are therefore needed to better address the effects of noncomplia...
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Full title
Using the Instrumental Variables Estimator to Analyze Noninferiority Trials with Noncompliance
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Record Identifier
TN_cdi_proquest_miscellaneous_733559918
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733559918
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ISSN
1054-3406
E-ISSN
1520-5711
DOI
10.1080/10543401003618157