A rationally designed heparin, M118, has anticoagulant activity similar to unfractionated heparin an...
A rationally designed heparin, M118, has anticoagulant activity similar to unfractionated heparin and different from Lovenox in a cell-based model of thrombin generation
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Publisher
Boston: Springer US
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Language
English
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Boston: Springer US
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Contents
Unfractionated heparin (UFH) enhances antithrombin (AT) inhibition of thrombin (IIa) and factor Xa (FXa). Low molecular weight heparins (LMWH) primarily enhance AT inhibition of FXa. M118 is a LMWH produced from UFH and retains its ability to promote both FXa and IIa inhibition. We tested the hypothesis that M118 has anticoagulant activities simila...
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Full title
A rationally designed heparin, M118, has anticoagulant activity similar to unfractionated heparin and different from Lovenox in a cell-based model of thrombin generation
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Record Identifier
TN_cdi_proquest_miscellaneous_733569196
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733569196
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ISSN
0929-5305,1573-742X
E-ISSN
1573-742X
DOI
10.1007/s11239-009-0360-0
