Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Patients with Duchenne muscular dystrophy (DMD) have a progressive dilated cardiomyopathy associated with fatal cardiac arrhythmias. Electrical and functional abnormalities have been attributed to cardiac fibrosis; however, electrical abnormalities may occur in the absence of overt cardiac histopathology. Here we show that structural and functional...
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Full title
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy
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Record Identifier
TN_cdi_proquest_miscellaneous_733618231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733618231
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0908540107