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Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733618231

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

About this item

Full title

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (4), p.1559-1564

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Patients with Duchenne muscular dystrophy (DMD) have a progressive dilated cardiomyopathy associated with fatal cardiac arrhythmias. Electrical and functional abnormalities have been attributed to cardiac fibrosis; however, electrical abnormalities may occur in the absence of overt cardiac histopathology. Here we show that structural and functional...

Alternative Titles

Full title

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733618231

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733618231

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0908540107

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