Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic pat...
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
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Publisher
Basingstoke: Elsevier Inc
Journal title
Language
English
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Publisher
Basingstoke: Elsevier Inc
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Scope and Contents
Contents
Fibroblast growth factor 23 (FGF23) exerts its effect by binding to its cognate FGF receptor 1 (FGFR1) in the presence of its co-receptor Klotho. Parathyroid glands express both FGFR1 and Klotho, and FGF23 decreases parathyroid hormone gene expression and hormone secretion directly. In uremic patients with secondary hyperparathyroidism (SHPT), howe...
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Full title
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
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TN_cdi_proquest_miscellaneous_733620111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733620111
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2009.414
