Prostaglandin E2–EP4 signaling initiates skin immune responses by promoting migration and maturation...
Prostaglandin E2–EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Antigen-specific immune responses in the skin are initiated by antigen uptake into Langerhans cells and the subsequent migration of these cells to draining lymph nodes. Although prostaglandin E
2
(PGE
2
) is produced substantially in skin exposed to antigen, its role remains unclear. Here we show that although Langerhans cells express a...
Alternative Titles
Full title
Prostaglandin E2–EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_73364419
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73364419
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm872