An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The authors report that the mRNA for myo-inositol monophosphatase-1, an enzyme that regulates the inositol cycle and the main target of lithium in neurons, is localized to axons. They identify a novel NGF-responsive localization element within the 3′ UTR that directs this targeting and local translation.
mRNA localization is an evolutionary cons...
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An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
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TN_cdi_proquest_miscellaneous_733660742
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733660742
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2486