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An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733660742

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

About this item

Full title

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2010-03, Vol.13 (3), p.291-301

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The authors report that the mRNA for myo-inositol monophosphatase-1, an enzyme that regulates the inositol cycle and the main target of lithium in neurons, is localized to axons. They identify a novel NGF-responsive localization element within the 3′ UTR that directs this targeting and local translation.
mRNA localization is an evolutionary cons...

Alternative Titles

Full title

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733660742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733660742

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.2486

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