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Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mou...

Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mou...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733687776

Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mouse model of COPD

About this item

Full title

Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mouse model of COPD

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2010-03, Vol.3 (3-4), p.246-253

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Cigarette smoking has been identified as one of the major risk factors and several predisposing genetic factors have been implicated in the pathogenesis of COPD, including a single nucleotide polymorphism (SNP) in the latent transforming growth fac...

Alternative Titles

Full title

Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mouse model of COPD

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733687776

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733687776

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.004234

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