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Oxidation of Free L-histidine by tert-Butylhydroperoxide

Oxidation of Free L-histidine by tert-Butylhydroperoxide

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733698415

Oxidation of Free L-histidine by tert-Butylhydroperoxide

About this item

Full title

Oxidation of Free L-histidine by tert-Butylhydroperoxide

Publisher

Boston: Boston : Springer US

Journal title

Pharmaceutical research, 2010-03, Vol.27 (3), p.447-456

Language

English

Formats

Publication information

Publisher

Boston: Boston : Springer US

More information

Scope and Contents

Contents

Purpose L-histidine, a commonly used buffer for protein formulations, has the potential to oxidize and form multiple byproducts. Previous studies were performed using metal catalyzed oxidation with Fe²⁺ or Cu²⁺. We re-examined the oxidation of L-histidine under conditions more appropriate to protein formulations. Methods Solutions of free L-histidi...

Alternative Titles

Full title

Oxidation of Free L-histidine by tert-Butylhydroperoxide

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733698415

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733698415

Other Identifiers

ISSN

0724-8741

E-ISSN

1573-904X

DOI

10.1007/s11095-009-0032-y

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