Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The bacterial protease ClpP forms an active complex with Clp-ATPases, but can also be directly activated by a recently characterized class of antibiotics (ADEP). Now the crystal structures of
Bacillus subtilis
ClpP bound to ADEPs reveal the conformational changes involved in ClpP's activation.
Clp-family proteins are prototypes for studyin...
Alternative Titles
Full title
Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_733855449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733855449
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.1787
