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Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth o...

Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733882781

Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma

About this item

Full title

Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Cancer chemotherapy and pharmacology, 2010-05, Vol.66 (1), p.79-87

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Purpose
We evaluated the involvement of angiotensin II (AngII)-dependent pathways in melanoma growth, through the pharmacological blockage of AT1 receptor by the anti-hypertensive drug losartan (LOS).
Results
We showed immunolabeling for both AngII and the AT1 receptor within the human melanoma microenvironment. Like human melanomas, we sh...

Alternative Titles

Full title

Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733882781

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733882781

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-009-1136-0

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