The Interaction of TIGIT with PVR and PVRL2 Inhibits Human NK Cell Cytotoxicity
The Interaction of TIGIT with PVR and PVRL2 Inhibits Human NK Cell Cytotoxicity
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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NK cell cytotoxicity is controlled by numerous NK inhibitory and activating receptors. Most of the inhibitory receptors bind MHC class I proteins and are expressed in a variegated fashion. It was recently shown that TIGIT, a new protein expressed by T and NK cells binds to PVR and PVR-like receptors and inhibits T cell activity indirectly through t...
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The Interaction of TIGIT with PVR and PVRL2 Inhibits Human NK Cell Cytotoxicity
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TN_cdi_proquest_miscellaneous_733903395
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733903395
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0903474106