KRAS Testing and Its Importance in Colorectal Cancer
KRAS Testing and Its Importance in Colorectal Cancer
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Publisher
New York: Current Science Inc
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Language
English
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Publisher
New York: Current Science Inc
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Contents
Cetuximab and panitumumab are monoclonal antibodies used in the treatment of metastatic colorectal cancer (mCRC) by selectively targeting the epidermal growth factor receptor (EGFR) axis. Studies have shown that mutations in codons 12/13 of exon 2 of the KRAS gene render these therapies ineffective. As a result, the National Comprehensive Cancer Ne...
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KRAS Testing and Its Importance in Colorectal Cancer
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TN_cdi_proquest_miscellaneous_733924095
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733924095
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ISSN
1523-3790
E-ISSN
1534-6269
DOI
10.1007/s11912-010-0099-y