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KRAS Testing and Its Importance in Colorectal Cancer

KRAS Testing and Its Importance in Colorectal Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733924095

KRAS Testing and Its Importance in Colorectal Cancer

About this item

Full title

KRAS Testing and Its Importance in Colorectal Cancer

Publisher

New York: Current Science Inc

Journal title

Current oncology reports, 2010-05, Vol.12 (3), p.160-167

Language

English

Formats

Publication information

Publisher

New York: Current Science Inc

More information

Scope and Contents

Contents

Cetuximab and panitumumab are monoclonal antibodies used in the treatment of metastatic colorectal cancer (mCRC) by selectively targeting the epidermal growth factor receptor (EGFR) axis. Studies have shown that mutations in codons 12/13 of exon 2 of the KRAS gene render these therapies ineffective. As a result, the National Comprehensive Cancer Ne...

Alternative Titles

Full title

KRAS Testing and Its Importance in Colorectal Cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733924095

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733924095

Other Identifiers

ISSN

1523-3790

E-ISSN

1534-6269

DOI

10.1007/s11912-010-0099-y

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