Kinetics of Zn(2+)-induced brain type creatine kinase unfolding and aggregation
Kinetics of Zn(2+)-induced brain type creatine kinase unfolding and aggregation
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Author / Creator
Mu, Hang , Lü, Zhi-Rong , Park, Daeui , Kim, Byoung-Chul , Bhak, Jong , Zou, Fei , Yang, Jun-Mo , Li, Sen , Park, Yong-Doo , Zou, He-Chang and Zhou, Hai-Meng
Publisher
United States
Journal title
Language
English
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Publication information
Publisher
United States
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Scope and Contents
Contents
We studied the effect of Zn(2+) on the folding and aggregation of brain creatine kinase (CK-BB). We developed a method to purify CK-BB from rabbit brain and conducted inhibition kinetics and unfolding studies of CK-BB. Zn(2+) conspicuously aggregated and osmolytes, such as glycine and proline, were able to suppress the formation of aggregates and p...
Alternative Titles
Full title
Kinetics of Zn(2+)-induced brain type creatine kinase unfolding and aggregation
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Record Identifier
TN_cdi_proquest_miscellaneous_733936805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733936805
Other Identifiers
E-ISSN
1559-0291
DOI
10.1007/s12010-009-8574-3
