Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 1: Identification of its inhibito...
Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 1: Identification of its inhibitory subunit complexes and their roles
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Publisher
Boston: Boston : Springer US
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Language
English
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Publisher
Boston: Boston : Springer US
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Contents
Cyclic GMP phosphodiesterase (PDE) in bovine rod photoreceptor outer segments (OS) comprises a catalytic subunit complex (Pαβ) and two inhibitory subunits (Pγ) and is regulated by the α subunit of transducin (Tα). Here, we show an overall mechanism for PDE regulation by identifying Pγ complexes in OS homogenates prepared with an isotonic buffer. Be...
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Full title
Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 1: Identification of its inhibitory subunit complexes and their roles
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TN_cdi_proquest_miscellaneous_733958602
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733958602
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ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-010-0387-8
