miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
About this item
Full title
Author / Creator
Aqeilan, R I , Calin, G A and Croce, C M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
MicroRNAs (miRNAs) encoded by the
miR-15/16
cluster are known to act as tumor suppressors. Expression of these miRNAs inhibits cell proliferation, promotes apoptosis of cancer cells, and suppresses tumorigenicity both
in vitro
and
in vivo
.
miR-15a
and
miR-16-1
function by targeting multiple oncogenes, including
BCL...
Alternative Titles
Full title
miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_733972584
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733972584
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2009.69
