A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of...
A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes
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Author / Creator
Böhm, M , Locke, W J , Sutherland, R L , Kench, J G and Henshall, S M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
GATA-2, a member of the GATA family of transcription factors, is involved in androgen receptor (AR) signaling, however, little is known regarding its role in prostate cancer. Here, we report that GATA-2 is expressed in a substantial proportion of prostate cancers and that high expression of GATA-2 is associated with biochemical recurrence and dista...
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Full title
A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes
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Record Identifier
TN_cdi_proquest_miscellaneous_734111760
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734111760
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2009.243