Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Epiblasts regain pluripotency
The pluripotent state, first established in the primitive ectoderm cells of the blastocyst-stage embryo, is lost during subsequent development. Bao
et al
. now show that advanced post-implantation epiblast cells from mouse embryos aged up to 7.5 days can be reprogrammed back to pluripotency by exposure to LIF/...
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Full title
Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
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TN_cdi_proquest_miscellaneous_734111900
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734111900
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08534
