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Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induce...

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734134804

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL‐12

About this item

Full title

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL‐12

Publisher

United States: Nature Publishing Group

Journal title

Immunology and cell biology, 2009-11, Vol.87 (8), p.590-600

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

T follicular helper (TFH) cells are a specialized subset of CD4+ T cells that localize to B‐cell follicles, where they are positioned to provide help for the induction of optimal humoral immune responses. Key features of TFH cells are the expressions of CXCR5, ICOS, interleukin (IL)‐21 and BCL‐6. The requirements for human TFH cell development are...

Alternative Titles

Full title

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL‐12

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_734134804

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734134804

Other Identifiers

ISSN

0818-9641

E-ISSN

1440-1711

DOI

10.1038/icb.2009.64

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