Spindle Assembly Checkpoint Protein Functions in Prophase I Arrest and Prometaphase Progression
Spindle Assembly Checkpoint Protein Functions in Prophase I Arrest and Prometaphase Progression
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Two critical stages of mammalian oocyte regulation are prophase I arrest, which is important for sustaining the oocyte pool, and the progression through meiosis I (MI) to produce fertilizable eggs. We have found that the spindle assembly checkpoint protein BubR1 regulates both stages in mouse oocytes. We show that oocytes depleted of BubR1 cannot s...
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Full title
Spindle Assembly Checkpoint Protein Functions in Prophase I Arrest and Prometaphase Progression
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Author / Creator
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TN_cdi_proquest_miscellaneous_734174918
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734174918
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1175326
