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Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Mode...

Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Mode...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734204280

Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Model of Apert Syndrome

About this item

Full title

Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Model of Apert Syndrome

Publisher

New York: Nature Publishing Group US

Journal title

Pediatric research, 2009-10, Vol.66 (4), p.386-390

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Patients with Apert syndrome (AS) display a wide range of congenital malformations including tracheal stenosis, which is a disease characterized by a uniform cartilaginous sleeve in place of a normally ribbed cartilagenous trachea. We have studied the cellular and molecular basis of this phenotype in a mouse model of AS (
Fgfr2c
+/Δ
mice),...

Alternative Titles

Full title

Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Model of Apert Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_734204280

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734204280

Other Identifiers

ISSN

0031-3998

E-ISSN

1530-0447

DOI

10.1203/PDR.0b013e3181b45580

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