Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Mode...
Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Model of Apert Syndrome
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Patients with Apert syndrome (AS) display a wide range of congenital malformations including tracheal stenosis, which is a disease characterized by a uniform cartilaginous sleeve in place of a normally ribbed cartilagenous trachea. We have studied the cellular and molecular basis of this phenotype in a mouse model of AS (
Fgfr2c
+/Δ
mice),...
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Fibroblast Growth Factor 10 Plays a Causative Role in the Tracheal Cartilage Defects in a Mouse Model of Apert Syndrome
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TN_cdi_proquest_miscellaneous_734204280
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734204280
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ISSN
0031-3998
E-ISSN
1530-0447
DOI
10.1203/PDR.0b013e3181b45580