Proton Pump Inhibitor and Clopidogrel Interaction: Fact or Fiction?
Proton Pump Inhibitor and Clopidogrel Interaction: Fact or Fiction?
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Basingstoke: Nature Publishing Group
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English
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Basingstoke: Nature Publishing Group
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Current consensus recommendations state that patients prescribed clopidogrel plus aspirin should receive a proton pump inhibitor (PPI) to reduce gastrointestinal bleeding. Clopidogrel is converted to its active metabolite by cytochrome P450 (CYP) enzymes. Clopidogrel users with decreased CYP2C19 function have less inhibition of platelet aggregation...
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Proton Pump Inhibitor and Clopidogrel Interaction: Fact or Fiction?
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TN_cdi_proquest_miscellaneous_734222717
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734222717
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ISSN
0002-9270
E-ISSN
1572-0241
DOI
10.1038/ajg.2009.638