Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
About this item
Full title
Author / Creator
van Amerongen, R , Nawijn, M C , Lambooij, J -P , Proost, N , Jonkers, J and Berns, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Wnt-signal transduction is critical for development and tissue homeostasis in a wide range of animal species and is frequently deregulated in human cancers. Members of the Frat/GBP family of glycogen synthase kinase 3β (Gsk3b)-binding oncoproteins are recognized as potent activators of the Wnt/β-catenin pathway in vertebrates. Here, we reveal a nov...
Alternative Titles
Full title
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_734222958
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734222958
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2009.310
