Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expressi...
Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation
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Publisher
Heidelberg: Springer
Journal title
Language
English
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Publisher
Heidelberg: Springer
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Contents
The left ends of the biosynthetic gene clusters of novobiocin ( nov), clorobiocin ( clo) and coumermycin A(1) ( cou) from Streptomyces spheroides (syn. S. caeruleus) NCIMB 11891, S. roseochromogenes var. oscitans DS 12.976 and S. rishiriensis DSM 40489 were cloned and sequenced. Sequence comparison suggested that novE, cloE and couE, respectively,...
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Full title
Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation
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TN_cdi_proquest_miscellaneous_73423004
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73423004
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ISSN
0302-8933
E-ISSN
1432-072X
DOI
10.1007/s00203-003-0555-2
