Requirement of Prorenin Receptor and Vacuolar H⁺ -ATPase-Mediated Acidification for Wnt Signaling
Requirement of Prorenin Receptor and Vacuolar H⁺ -ATPase-Mediated Acidification for Wnt Signaling
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Wnt/ß-catenin signaling is important in stem cell biology, embryonic development, and disease, including cancer. However, the mechanism of Wnt signal transmission, notably how the receptors are activated, remains incompletely understood. We found that the prorenin receptor (PRR) is a component of the Wnt receptor complex. PRR functions in a renin-i...
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Full title
Requirement of Prorenin Receptor and Vacuolar H⁺ -ATPase-Mediated Acidification for Wnt Signaling
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TN_cdi_proquest_miscellaneous_734253201
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734253201
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1179802
