Immunogenic death of colon cancer cells treated with oxaliplatin
Immunogenic death of colon cancer cells treated with oxaliplatin
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Author / Creator
Tesniere, A , Schlemmer, F , Boige, V , Kepp, O , Martins, I , Ghiringhelli, F , Aymeric, L , Michaud, M , Apetoh, L , Barault, L , Mendiboure, J , Pignon, J-P , Jooste, V , van Endert, P , Ducreux, M , Zitvogel, L , Piard, F and Kroemer, G
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Both the pre-apoptotic exposure of calreticulin (CRT) and the post-apoptotic release of high-mobility group box 1 protein (HMGB1) are required for immunogenic cell death elicited by anthracyclins. Here, we show that both oxaliplatin (OXP) and cisplatin (CDDP) were equally efficient in triggering HMGB1 release. However, OXP, but not CDDP, stimulates...
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Full title
Immunogenic death of colon cancer cells treated with oxaliplatin
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Record Identifier
TN_cdi_proquest_miscellaneous_734259774
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734259774
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2009.356