Mutations in the Clathrin-Assembly Gene Picalm Are Responsible for the Hematopoietic and Iron Metabo...
Mutations in the Clathrin-Assembly Gene Picalm Are Responsible for the Hematopoietic and Iron Metabolism Abnormalities in fit1 Mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Recessive N-ethyl-N-nitrosourea (ENU)-induced mutations recovered at the fitness-1 (fit1) locus in mouse chromosome 7 cause hematopoietic abnormalities, growth retardation, and shortened life span, with varying severity of the defects in different alleles. Abnormal iron distribution and metabolism and frequent scoliosis have also been associated wi...
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Full title
Mutations in the Clathrin-Assembly Gene Picalm Are Responsible for the Hematopoietic and Iron Metabolism Abnormalities in fit1 Mice
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TN_cdi_proquest_miscellaneous_73440923
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73440923
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1432634100
