HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
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Author / Creator
Kollet, Orit , Shivtiel, Shoham , Chen, Yuan-Qing , Suriawinata, Jenny , Thung, Swan N , Dabeva, Mariana D , Kahn, Joy , Spiegel, Asaf , Dar, Ayelet , Samira, Sarit , Goichberg, Polina , Kalinkovich, Alexander , Arenzana-Seisdedos, Fernando , Nagler, Arnon , Hardan, Izhar , Revel, Michel , Shafritz, David A and Lapidot, Tsvee
Publisher
United States
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Language
English
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Publisher
United States
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Contents
Hematopoietic stem cells rarely contribute to hepatic regeneration, however, the mechanisms governing their homing to the liver, which is a crucial first step, are poorly understood. The chemokine stromal cell-derived factor-1 (SDF-1), which attracts human and murine progenitors, is expressed by liver bile duct epithelium. Neutralization of the SDF...
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Full title
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
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TN_cdi_proquest_miscellaneous_73462757
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73462757
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ISSN
0021-9738
DOI
10.1172/jci17902
