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Acquired von Willebrand Syndrome in Aortic Stenosis

Acquired von Willebrand Syndrome in Aortic Stenosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73511756

Acquired von Willebrand Syndrome in Aortic Stenosis

About this item

Full title

Acquired von Willebrand Syndrome in Aortic Stenosis

Publisher

Boston, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2003-07, Vol.349 (4), p.343-349

Language

English

Formats

Publication information

Publisher

Boston, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

Some patients with aortic stenosis have a bleeding tendency that may result, as this study shows, from an acquired form of von Willebrand syndrome. High shear forces at the stenotic valve change the shape of the von Willebrand protein, resulting in proteolysis, loss of the largest multimers, and reduction in platelet adhesion to the vascular endoth...

Alternative Titles

Full title

Acquired von Willebrand Syndrome in Aortic Stenosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73511756

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73511756

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa022831

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