Acquired von Willebrand Syndrome in Aortic Stenosis
Acquired von Willebrand Syndrome in Aortic Stenosis
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Publisher
Boston, MA: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
Some patients with aortic stenosis have a bleeding tendency that may result, as this study shows, from an acquired form of von Willebrand syndrome. High shear forces at the stenotic valve change the shape of the von Willebrand protein, resulting in proteolysis, loss of the largest multimers, and reduction in platelet adhesion to the vascular endoth...
Alternative Titles
Full title
Acquired von Willebrand Syndrome in Aortic Stenosis
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Record Identifier
TN_cdi_proquest_miscellaneous_73511756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73511756
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa022831