T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on t...
T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells
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Full title
Author / Creator
Heuser, C , Hombach, A , Lösch, C , Manista, K and Abken, H
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Recombinant immunoreceptors are modularily composed of extracellular antigen binding and intracellular signalling domains that are preferentially derived from CD3ζ or FcɛRIγ. The impact of the signalling domain on the stability of immuoreceptor expression and function is not completely understood. To address this issue, we generated and expressed a...
Alternative Titles
Full title
T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_73547039
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73547039
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ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/sj.gt.3302023