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T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on t...

T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73547039

T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells

About this item

Full title

T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells

Publisher

London: Nature Publishing Group UK

Journal title

Gene therapy, 2003-08, Vol.10 (17), p.1408-1419

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recombinant immunoreceptors are modularily composed of extracellular antigen binding and intracellular signalling domains that are preferentially derived from CD3ζ or FcɛRIγ. The impact of the signalling domain on the stability of immuoreceptor expression and function is not completely understood. To address this issue, we generated and expressed a...

Alternative Titles

Full title

T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73547039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73547039

Other Identifiers

ISSN

0969-7128

E-ISSN

1476-5462

DOI

10.1038/sj.gt.3302023

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