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VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons agai...

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons agai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73583990

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

Publication information

Publisher

New York: Nature Publishing Group US

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is an incurable degenerative disorder of motoneurons. We recently reported that reduced expression of
Vegfa
causes ALS-like motoneuron degeneration in
Vegfa
δ/δ
mice. In a meta-analysis of over 900 individuals from Sweden and over 1,000 individuals from Belgium and England, we now report that subje...

Alternative Titles

Full title

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73583990

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73583990

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng1211

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