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Costimulation through the inducible costimulator ligand is essential for both T helper and B cell fu...

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell fu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73601898

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses

About this item

Full title

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2003-08, Vol.4 (8), p.765-772

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Costimulation through the inducible costimulator (ICOS) and its ligand (ICOSL) is essential for T cell–dependent B cell responses, but the cellular and temporal dynamics underlying its
in vivo
effects are poorly defined. Here we have shown that
Icosl
−/−
and
Icos
−/−
mice had similar phenotypes and that ICOS-ICOSL costimulat...

Alternative Titles

Full title

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73601898

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73601898

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni947

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