Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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SHP-2 tyrosine phosphatase is highly expressed in hematopoietic cells, however, the function of SHP-2 in hematopoietic cell signaling is not well understood. Here we focus on the role of SHP-2 phosphatase in the signal transduction of interleukin (IL)-3, a cytokine involved in hematopoietic cell survival, proliferation, and differentiation. We esta...
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Full title
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
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TN_cdi_proquest_miscellaneous_73637008
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73637008
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206846
