Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3′→2′) Oligonucleotide System
Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3′→2′) Oligonucleotide System
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Washington, DC: American Society for the Advancement of Science
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English
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Washington, DC: American Society for the Advancement of Science
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TNAs [(L)-α-threofuranosyl oligonucleotides] containing vicinally connected (3′→2′) phosphodiester bridges undergo informational base pairing in antiparallel strand orientation and are capable of cross-pairing with RNA and DNA. Being derived from a sugar containing only four carbons, TNA is structurally the simplest of all potentially natural oligo...
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Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3′→2′) Oligonucleotide System
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TN_cdi_proquest_miscellaneous_743116572
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743116572
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.290.5495.1347
