Control of MHC restriction by TCR Valpha CDR1 and CDR2
Control of MHC restriction by TCR Valpha CDR1 and CDR2
About this item
Full title
Author / Creator
Sim, B C , Zerva, L , Greene, M I and Gascoigne, N R
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Individual T cell receptor (TCR) Valpha elements are expressed preferentially in CD4 or CD8 peripheral T cell subsets. The closely related Valpha3.1 and Valpha3.2 elements show reciprocal selection into CD4 and CD8 subsets, respectively. Transgenic mice expressing site-directed mutants of a Valpha3.1 gene were used to show that individual residues...
Alternative Titles
Full title
Control of MHC restriction by TCR Valpha CDR1 and CDR2
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_743149029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743149029
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.273.5277.963