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Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743156908

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

About this item

Full title

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2008-09, Vol.321 (5895), p.1493-1495

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

There is substantial interest in the development of drugs that limit the extent of ischemia-induced cardiac damage caused by myocardial infarction or by certain surgical procedures. Here, using an unbiased proteomic search, we identified mitochondrial aldehyde dehydrogenase 2 (ALDH2) as an enzyme whose activation correlates with reduced ischemic he...

Alternative Titles

Full title

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743156908

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743156908

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1158554

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