Functions of FGF signalling from the apical ectodermal ridge in limb development
Functions of FGF signalling from the apical ectodermal ridge in limb development
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
To determine the role of fibroblast growth factor (FGF) signalling from the apical ectodermal ridge (AER), we inactivated
Fgf4
and
Fgf8
in AER cells or their precursors at different stages of mouse limb development. We show that FGF4 and FGF8 regulate cell number in the nascent limb bud and are required for survival of cells located far...
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Full title
Functions of FGF signalling from the apical ectodermal ridge in limb development
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TN_cdi_proquest_miscellaneous_743203178
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743203178
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature00902