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Functions of FGF signalling from the apical ectodermal ridge in limb development

Functions of FGF signalling from the apical ectodermal ridge in limb development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743203178

Functions of FGF signalling from the apical ectodermal ridge in limb development

About this item

Full title

Functions of FGF signalling from the apical ectodermal ridge in limb development

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2002-08, Vol.418 (6897), p.501-508

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

To determine the role of fibroblast growth factor (FGF) signalling from the apical ectodermal ridge (AER), we inactivated
Fgf4
and
Fgf8
in AER cells or their precursors at different stages of mouse limb development. We show that FGF4 and FGF8 regulate cell number in the nascent limb bud and are required for survival of cells located far...

Alternative Titles

Full title

Functions of FGF signalling from the apical ectodermal ridge in limb development

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743203178

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743203178

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature00902

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