Modulation of ATP-Dependent Chromatin-Remodeling Complexes by Inositol Polyphosphates
Modulation of ATP-Dependent Chromatin-Remodeling Complexes by Inositol Polyphosphates
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Author / Creator
Shen, Xuetong , Xiao, Hua , Ranallo, Ryan , Wu, Wei-Hua and Wu, Carl
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Eukaryotes use adenosine triphosphate (ATP)-dependent chromatin-remodeling complexes to regulate gene expression. Here, we show that inositol polyphosphates can modulate the activities of several chromatin-remodeling complexes in vitro. Inositol hexakisphosphate (IP6) inhibits nucleosome mobilization by NURF, ISW2, and INO80 complexes. In contrast,...
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Full title
Modulation of ATP-Dependent Chromatin-Remodeling Complexes by Inositol Polyphosphates
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Record Identifier
TN_cdi_proquest_miscellaneous_743297117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743297117
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1078068
