Untangling Checkpoints
Untangling Checkpoints
About this item
Full title
Author / Creator
Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Scientists believe that Chk1 and Cds1 phosphorylate and inhibit Cdc25C, a phosphatase that directly activates the Cdk1-cyclin B complex, thereby preventing the cell from entering mitosis. A recent study reveals that Chk1 regulates the stability of Cdc25A, another member of the Cdc25 family, at multiple cell cycle checkpoints in vertebrate cells.
Alternative Titles
Full title
Untangling Checkpoints
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_743345302
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743345302
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1079225
